Primary Identifier | MGI:1334203 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 16533 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables calcium-activated potassium channel activity. Acts upstream of or within potassium ion transmembrane transport. Located in membrane. Part of voltage-gated potassium channel complex. Is expressed in arterial system; sensory organ; skeleton; and tarsus. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human KCNMB1 (potassium calcium-activated channel subfamily M regulatory beta subunit 1). PHENOTYPE: Homozygous mutation of this gene results in increased blood pressure, and impaired motor coordination and cerebellar function. [provided by MGI curators] |