Primary Identifier | MGI:2388637 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 211652 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable kinase binding activity and transcription coactivator activity. Predicted to be involved in several processes, including negative regulation of organ growth; negative regulation of transcription by RNA polymerase II; and regulation of intracellular signal transduction. Located in cytoplasm. Is expressed in female associated reproductive structure; forelimb bud ectoderm; retina; ureteric tip; and ureteric trunk. Orthologous to human WWC1 (WW and C2 domain containing 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired adult synaptic plasticity and fear-based conditioning. [provided by MGI curators] |