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Protein Coding Gene : Wwc1 WW, C2 and coiled-coil domain containing 1

Primary Identifier  MGI:2388637 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  211652
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable kinase binding activity and transcription coactivator activity. Predicted to be involved in several processes, including negative regulation of organ growth; negative regulation of transcription by RNA polymerase II; and regulation of intracellular signal transduction. Located in cytoplasm. Is expressed in female associated reproductive structure; forelimb bud ectoderm; retina; ureteric tip; and ureteric trunk. Orthologous to human WWC1 (WW and C2 domain containing 1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired adult synaptic plasticity and fear-based conditioning. [provided by MGI curators]
  • synonyms:
  • expressed sequence AU017197,
  • BC037006,
  • AU017197,
  • WW, C2 and coiled-coil domain containing 1,
  • Kibra,
  • AA408228,
  • MGI:2144380,
  • MGC:47054,
  • Wwc1,
  • MGI:2143978,
  • expressed sequence AA408228,
  • cDNA sequence BC037006

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For