| Primary Identifier | MGI:1926194 | Organism | Mus musculus |
| Chromosome | 11 | NCBI Gene Number | 57783 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 3.1.1) Exhibits polyubiquitin modification-dependent protein binding activity. Involved in several processes, including MyD88-dependent toll-like receptor signaling pathway; negative regulation of I-kappaB kinase/NF-kappaB signaling; and positive regulation of transcription by RNA polymerase II. Localizes to cytoplasm. Is expressed in gonad; ovary; seminiferous cord; and thymus primordium. Orthologous to human TNIP1 (TNFAIP3 interacting protein 1). PHENOTYPE: Mice homozygous for a null allele exhibit perinatal lethality associated with anemia and focal apoptosis in the fetal liver. Mice homozygous for a gene trap allele exhibit partial prenatal lethality and SLE-like inflammatory disease. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
