Primary Identifier | MGI:1919173 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 71923 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable identical protein binding activity. Predicted to be involved in lysosome localization. Predicted to be located in lysosome and membrane. Predicted to be part of BORC complex. Is expressed in several structures, including alimentary system; brain; egg cylinder; genitourinary system; and hemolymphoid system. Orthologous to human BORCS6 (BLOC-1 related complex subunit 6). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased embryo size, egg cylinder degeneration, failure of primitive streak formation, absent primitive node and head folds, failure to gastrulate, and complete lethality prior to organogenesis. [provided by MGI curators] |