| Primary Identifier | MGI:2144284 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 103844 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables cyclin binding activity. Acts upstream of or within negative regulation of fibroblast proliferation and positive regulation of apoptotic signaling pathway. Predicted to be located in nuclear body. Predicted to be active in cytoplasm. Is expressed in female reproductive system; germ cell of ovary; mesenchymal stroma of ovary; and ovary. Orthologous to human INCA1 (inhibitor of CDK, cyclin A1 interacting protein 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased cell proliferation in mouse embryonic fibroblasts and older mice exhibit abnormal spleen architecture, particularly in the white pulp, and extramedullary hematopoiesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
