| Primary Identifier | MGI:2151483 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 116891 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable signal recognition particle binding activity. Acts upstream of or within retrograde protein transport, ER to cytosol and suckling behavior. Located in early endosome; endoplasmic reticulum; and late endosome. Is expressed in yolk sac and yolk sac endoderm. Orthologous to human DERL2 (derlin 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit partial neonatal lethality with surviving mice exhibiting male sterility, inverted rib cage, abnormal chondrocytes in the ribs, lethality during pregancy, cachexia, and premature death. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
