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Protein Coding Gene : Rph3al rabphilin 3A-like (without C2 domains)

Primary Identifier  MGI:1923492 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  380714
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable LIM domain binding activity. Involved in glucose homeostasis and positive regulation of insulin secretion. Acts upstream of or within negative regulation of G protein-coupled receptor signaling pathway and regulation of calcium ion-dependent exocytosis. Predicted to be located in secretory granule. Predicted to be active in synapse. Orthologous to human RPH3AL (rabphilin 3A like (without C2 domains)).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit disregulation of exocytosis in both endocrine and exocrine cells. [provided by MGI curators]
  • synonyms:
  • MGI:2686599,
  • Rph3al,
  • AI551877,
  • RIKEN cDNA 6530413F01 gene,
  • gene model 1753, (NCBI),
  • MGI:2144220,
  • LOC385671,
  • Gm1753,
  • 6530413F01Rik,
  • expressed sequence AI551877,
  • rabphilin 3A-like (without C2 domains),
  • Noc2

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

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2 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Expression

Gene --> Expression annotations

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Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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