| Primary Identifier | MGI:1202880 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 22032 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables protein kinase binding activity. Acts upstream of or within respiratory gaseous exchange by respiratory system and respiratory tube development. Predicted to be located in cytosol; fibrillar center; and nucleoplasm. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; branchial arch mesenchyme derived from neural crest; central nervous system; genitourinary system; and sensory organ. Orthologous to human TRAF4 (TNF receptor associated factor 4). PHENOTYPE: Homozygotes for targeted null mutations show respiratory problems, various skeletal defects, spina bifida and partial lethality around embryonic day 14. Homozygotes for an ENU-induced mutation exhibit postnatal lethality and hypopigmentation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
