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Protein Coding Gene : Aldoc aldolase C, fructose-bisphosphate

Primary Identifier  MGI:101863 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  11676
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables fructose-bisphosphate aldolase activity. Involved in gluconeogenesis. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autoimmune disease of the nervous system. Orthologous to human ALDOC (aldolase, fructose-bisphosphate C).
PHENOTYPE: Mice homozygous for a knock-out allele show decreased plasma levels of total cholesterol and HDL cholesterol in both sexes and decreased plasma triglyceride levels in females. [provided by MGI curators]
  • synonyms:
  • MGI:2144291,
  • Scrg2,
  • AI847350,
  • scrapie responsive gene 2,
  • expressed sequence AU040929,
  • Aldoc,
  • expressed sequence AI847350,
  • MGI:1328309,
  • aldolase C, fructose-bisphosphate,
  • MGD-MRK-18688,
  • zebrin II,
  • Aldolase C,
  • AU040929,
  • Aldo3,
  • MGI:2144424

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For