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Protein Coding Gene : Rffl ring finger and FYVE like domain containing protein

Primary Identifier  MGI:1914588 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  67338
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable enzyme binding activity; p53 binding activity; and ubiquitin protein ligase activity. Involved in regulation of fibroblast migration. Acts upstream of or within intracellular protein transport. Located in cytoplasmic vesicle. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system gland; liver; and retina nuclear layer. Orthologous to human RFFL (ring finger and FYVE like domain containing E3 ubiquitin protein ligase).
PHENOTYPE: Mice homozygous for an inactivating targeted mutation of this gene are born at the expected Mendelian frequency; they are viable and fertile and exhibit no apparent abnormal phenotype. [provided by MGI curators]
  • synonyms:
  • Rffl,
  • Carp-2,
  • BG080975,
  • MGI:2671013,
  • ring finger and FYVE like domain containing protein,
  • RIKEN cDNA 4930516L10 gene,
  • RIKEN cDNA 1700051E09 gene,
  • expressed sequence BG080975,
  • rififylin,
  • 4930516L10Rik,
  • 1700051E09Rik,
  • MGI:1922384,
  • fring,
  • Carp2

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For