| Primary Identifier | MGI:96190 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 15417 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Contributes to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including embryonic skeletal system development; mammary gland development; and positive regulation of transcription by RNA polymerase II. Part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including central nervous system; early embryo; embryo mesenchyme; genitourinary system; and gut. Orthologous to human HOXB9 (homeobox B9). PHENOTYPE: Mutations affect developing thoracic skeletal elements. Homozygotes exhibit rib fusion, abnormal rib attachment to the sternum, and reduced intercostal segments of the sternum. Homozygotes or heterozygotes may show an eighth rib attached to the sternum. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
