| Primary Identifier | MGI:1933179 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 56013 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable protein domain specific binding activity and protein kinase binding activity. Involved in regulation of synapse assembly. Acts upstream of or within negative regulation of cell adhesion. Located in postsynaptic density. Is active in glutamatergic synapse and presynapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and respiratory system. Orthologous to human SRCIN1 (SRC kinase signaling inhibitor 1). PHENOTYPE: Mice homozygous for a knock-out allele display abnormalities in object recognition memory and motor learning, dendritic spine disorganization, impaired synaptic plasticity, and reduced long term potentiation and long term depression. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
