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Protein Coding Gene : Med24 mediator complex subunit 24

Primary Identifier  MGI:1344385 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  23989
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable histone acetyltransferase activity; nuclear thyroid hormone receptor binding activity; and transcription coactivator activity. Predicted to contribute to ubiquitin protein ligase activity. Acts upstream of or within somatic stem cell population maintenance and transcription by RNA polymerase II. Part of mediator complex. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; gut; and retina. Orthologous to human MED24 (mediator complex subunit 24).
PHENOTYPE: Homozygous mutant mice die prior to birth exhibiting abnormal heart development, neural tube defects, and anemia. [provided by MGI curators]
  • synonyms:
  • expressed sequence AU040102,
  • AU040102,
  • thyroid hormone receptor associated protein 4,
  • expressed sequence R75526,
  • Trap100,
  • Med24,
  • AW547152,
  • MGI:2144713,
  • mediator complex subunit 24,
  • genetic suppressor element 2,
  • 100kDa,
  • expressed sequence AW547152,
  • MGI:1098276,
  • Thrap4,
  • R75526,
  • MGI:1098829,
  • MGI:2144562,
  • MGI:2144420,
  • DNA segment, Chr 11, ERATO Doi 307, expressed,
  • Gse2,
  • D11Ertd307e,
  • DRIP100,
  • Pparb2

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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0 Driver For