Primary Identifier | MGI:1858222 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 53860 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable GTPase activity and molecular adaptor activity. Predicted to be involved in cytoskeleton-dependent cytokinesis and positive regulation of non-motile cilium assembly. Predicted to act upstream of or within cell division. Part of septin complex. Is expressed in several structures, including branchial arch; embryo ectoderm; embryo mesenchyme; inner ear; and integumental system. Human ortholog(s) of this gene implicated in brachial plexus neuritis and colorectal cancer. Orthologous to human SEPTIN9 (septin 9). PHENOTYPE: Mice homozygous for a targeted allele exhibit embryonic lethality around E10 with generalized apoptotic degeneration. [provided by MGI curators] |