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Protein Coding Gene : Cbx8 chromobox 8

Primary Identifier  MGI:1353589 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  30951
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables single-stranded RNA binding activity and ubiquitin-protein transferase activator activity. Predicted to be involved in positive regulation of cell population proliferation; positive regulation of collagen biosynthetic process; and regulation of nucleobase-containing compound metabolic process. Predicted to act upstream of or within heterochromatin formation. Located in nucleus. Part of PRC1 complex and heterochromatin. Is expressed in several structures, including brain. Orthologous to human CBX8 (chromobox 8).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired MLL-AF9 transformation but are otherwise viable with normal hematopoiesis. [provided by MGI curators]
  • synonyms:
  • polycomb 3,
  • Cbx8,
  • Pc3,
  • chromobox 8

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

13 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For