Primary Identifier | MGI:1929628 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 58185 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable 4 iron, 4 sulfur cluster binding activity. Involved in several processes, including defense response to virus; negative regulation of viral genome replication; and positive regulation of immune response. Located in endoplasmic reticulum and lipid droplet. Human ortholog(s) of this gene implicated in respiratory syncytial virus infectious disease. Orthologous to human RSAD2 (radical S-adenosyl methionine domain containing 2). PHENOTYPE: Mice homozygous for a null allele exhibit impaired T-helper 2 differentitation. [provided by MGI curators] |