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Protein Coding Gene : Zfp277 zinc finger protein 277

Primary Identifier  MGI:1890393 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  246196
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within cellular response to hydrogen peroxide and regulation of cellular senescence. Predicted to be located in chromosome; cytoplasm; and nucleus. Is expressed in early conceptus and genitourinary system. Orthologous to human ZNF277 (zinc finger protein 277).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit early cellular preplicative senescence in MEFs. [provided by MGI curators]
  • synonyms:
  • NIRF4,
  • Zfp277,
  • MGI:1922071,
  • zinc finger protein 277,
  • RIKEN cDNA 2410017E24 gene,
  • 2410017E24Rik

Features --> Cross References

Genome

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0 Involved In Mutations

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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