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Protein Coding Gene : Akap5 A kinase anchor protein 5

Primary Identifier  MGI:2685104 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  238276
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables adenylate cyclase binding activity and molecular adaptor activity. Involved in several processes, including neuronal ion channel clustering; postsynaptic neurotransmitter receptor cycle; and synapse assembly. Acts upstream of or within several processes, including amylase secretion; cellular response to calcium ion; and cellular response to xenobiotic stimulus. Located in cytoskeleton and plasma membrane. Is active in postsynaptic recycling endosome. Is expressed in brain. Orthologous to human AKAP5 (A-kinase anchoring protein 5).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced long term potentiation, improved glucose handling and heightened insulin sensitivity. [provided by MGI curators]
  • synonyms:
  • MGI:2145066,
  • expressed sequence BB098886,
  • MGI:1918024,
  • A kinase anchor protein 5,
  • 3526401B18Rik,
  • AKAP150,
  • RIKEN cDNA 3526401B18 gene,
  • BB098886,
  • Akap5,
  • gene model 258, (NCBI),
  • Gm258,
  • LOC238276

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For