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Protein Coding Gene : Entpd5 ectonucleoside triphosphate diphosphohydrolase 5
Primary Identifier  MGI:1321385 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  12499
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables GDP phosphatase activity and UDP phosphatase activity. Involved in UDP catabolic process. Acts upstream of with a positive effect on 'de novo' post-translational protein folding; UDP-glucose metabolic process; and protein N-linked glycosylation. Located in endoplasmic reticulum. Is expressed in several structures, including genitourinary system; gut; hemolymphoid system gland; liver; and nose. Orthologous to human ENTPD5 (ectonucleoside triphosphate diphosphohydrolase 5 (inactive)).
PHENOTYPE: Mice homozygous for a null allele develop progressive hepatopathy, hepatocellular tumors, and spermatogenic arrest. [provided by MGI curators]
  • synonyms:
  • NTPDase5,
  • expressed sequence AI196558,
  • ectonucleoside triphosphate diphosphohydrolase 5,
  • AI987697,
  • CD39 antigen-like 4,
  • Cd39l4,
  • MGI:2144919,
  • mNTPase,
  • ER-UDPase,
  • Entpd5,
  • Pcph,
  • MGI:2144773,
  • expressed sequence AI987697,
  • AI196558,
  • NTPDase-5
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1 Involved In Mutations

Trail: ProteinCodingGene

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0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

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Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

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Disease

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Trail: ProteinCodingGene




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