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Protein Coding Gene : Gpr65 G-protein coupled receptor 65

Primary Identifier  MGI:108031 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  14744
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; positive regulation of Rho protein signal transduction; and positive regulation of stress fiber assembly. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human GPR65 (G protein-coupled receptor 65).
PHENOTYPE: Homozygous mutant mice have thymocytes and splenocytes that are insensitive to pH-dependent cAMP production. [provided by MGI curators]
  • synonyms:
  • Dig1,
  • Gpcr25,
  • Gpr65,
  • MGD-MRK-37067,
  • TDAG8,
  • G-protein coupled receptor 25,
  • G-protein coupled receptor 65

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

2 Driver For