Primary Identifier | MGI:108031 | Organism | mouse, laboratory |
Chromosome | 12 | NCBI Gene Number | 14744 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable G protein-coupled receptor activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; positive regulation of Rho protein signal transduction; and positive regulation of stress fiber assembly. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human GPR65 (G protein-coupled receptor 65). PHENOTYPE: Homozygous mutant mice have thymocytes and splenocytes that are insensitive to pH-dependent cAMP production. [provided by MGI curators] |