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Protein Coding Gene : Ppp4r3a protein phosphatase 4 regulatory subunit 3A

Primary Identifier  MGI:1915984 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  68734
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable protein phosphatase activator activity. Acts upstream of or within positive regulation of gluconeogenesis. Located in cytoplasm and nucleus. Part of protein phosphatase 4 complex. Is expressed in several structures, including central nervous system; heart; and retina nuclear layer. Orthologous to human PPP4R3A (protein phosphatase 4 regulatory subunit 3A).
PHENOTYPE: Mice homozygous for a conditional allele exhibit increased anxiety- and depression-related behaviors with decreased miniature excitatory postsynaptic currents, decreased glutamate release, and decreased dendritic spine density. [provided by MGI curators]
  • synonyms:
  • 1110034C04Rik,
  • RIKEN cDNA 1110034C04 gene,
  • BC064465,
  • cDNA sequence BC064465,
  • Ppp4r3a,
  • SMEK homolog 1, suppressor of mek1 (Dictyostelium),
  • protein phosphatase 4 regulatory subunit 3A,
  • Smek1,
  • MGI:3037543

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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0 Driver For