|  Help  |  About  |  Contact Us

Protein Coding Gene : Exoc2 exocyst complex component 2

Primary Identifier  MGI:1913732 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  66482
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables small GTPase binding activity. Predicted to be involved in Golgi to plasma membrane transport; regulation of entry of bacterium into host cell; and vesicle docking involved in exocytosis. Predicted to act upstream of or within positive regulation of exocytosis. Predicted to be located in plasma membrane. Predicted to be part of exocyst. Is expressed in several structures, including central nervous system; early conceptus; genitourinary system; and palatal shelf. Orthologous to human EXOC2 (exocyst complex component 2).
PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality between implantation and somite formation and failure of blastocysts to hatch from the zona pellucida with increased cell death during outgrowth culture. [provided by MGI curators]
  • synonyms:
  • SEC5-like 1 (S. cerevisiae),
  • exocyst complex component 2,
  • AI648199,
  • MGI:5588834,
  • Sec5,
  • 2410030I24Rik,
  • Gm29675,
  • predicted gene, 29675,
  • expressed sequence AI648199,
  • Sec5l1,
  • RIKEN cDNA 2410030I24 gene,
  • MGI:2145277,
  • Exoc2

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For