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Protein Coding Gene : Acot12 acyl-CoA thioesterase 12
Primary Identifier  MGI:1921406 Organism  mouse, laboratory
Chromosome  13 NCBI Gene Number  74156
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables ATP binding activity and acetyl-CoA hydrolase activity. Acts upstream of or within acetyl-CoA metabolic process. Predicted to be located in intercellular bridge and nucleoplasm. Predicted to be active in cytosol. Is expressed in alimentary system and liver. Orthologous to human ACOT12 (acyl-CoA thioesterase 12).
PHENOTYPE: Mice homozygous for a null allele exhibit accelerated liver tumor formation in DEN/CCl4-induced and diet-induced hepatocarcinogenesis. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 4930449F15 gene,
  • AV027244,
  • Acot12,
  • MGI:2145388,
  • 4930449F15Rik,
  • cytosolic acetyl-CoA hydrolase,
  • RIKEN cDNA 1300004O04 gene,
  • Cach,
  • 1300004O04Rik,
  • expressed sequence AV027244,
  • acyl-CoA thioesterase 12,
  • MGI:1922149
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