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Protein Coding Gene : Oxgr1 oxoglutarate (alpha-ketoglutarate) receptor 1

Primary Identifier  MGI:2685145 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  239283
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable AMP binding activity; G protein-coupled adenosine receptor activity; and purine nucleoside binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in epididymis; metanephros; neural retina; and retina. Human ortholog(s) of this gene implicated in calcium oxalate nephrolithiasis. Orthologous to human OXGR1 (oxoglutarate receptor 1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit reduced leukotriene E4 ligand (LTE4)-induced ear edema at low and intermediate doses and abnormal acid-base balance. [provided by MGI curators]
  • synonyms:
  • Gpr99,
  • G protein-coupled receptor 80,
  • Cysltr3,
  • Gpr80,
  • oxoglutarate (alpha-ketoglutarate) receptor 1,
  • gene model 299, (NCBI),
  • Gm299,
  • LOC239283,
  • P2Y15,
  • Oxgr1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For