| Primary Identifier | MGI:107716 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 17909 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable cytoskeletal protein binding activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and plus-end directed microfilament motor activity. Acts upstream of or within positive regulation of cell-cell adhesion. Located in filopodium; neuron projection; and neuronal cell body. Is expressed in several structures, including autopod; central nervous system; genitourinary system; gut; and integumental system placode. Orthologous to human MYO10 (myosin X). PHENOTYPE: Homozygous null mutations are semi-lethal with over half of homozygous embryos exhibiting exencephaly. Surviving mutants show decreased body weight, white spotting, syndactyly, persistence of hyaloid vascular system and other eye defects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
