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Protein Coding Gene : Ebag9 estrogen receptor-binding fragment-associated gene 9
Primary Identifier  MGI:1859920 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  55960
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Acts upstream of or within T cell mediated cytotoxicity and adaptive immune memory response involving T cells and B cells. Located in Golgi apparatus. Is expressed in several structures, including central nervous system; genitourinary system; retina; spleen; and submandibular gland primordium epithelium. Human ortholog(s) of this gene implicated in breast cancer. Orthologous to human EBAG9 (estrogen receptor binding site associated antigen 9).
PHENOTYPE: Homozygous null mice have decreased susceptibility to bacterial infections and have CD8+ T cells with enhanced cytolytic activity. [provided by MGI curators]
  • synonyms:
  • AI835379,
  • MGI:2146065,
  • estrogen receptor-binding fragment-associated gene 9,
  • Rcas1,
  • Ebag9,
  • expressed sequence AI835379
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2 Involved In Mutations

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