| Primary Identifier | MGI:2146322 | Organism | mouse, laboratory |
| Chromosome | 15 | NCBI Gene Number | 97998 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable phosphatidic acid binding activity and protein serine/threonine kinase inhibitor activity. Predicted to be involved in several processes, including negative regulation of TOR signaling; negative regulation of cell size; and regulation of extrinsic apoptotic signaling pathway. Predicted to be located in lysosome and membrane. Predicted to be active in lysosomal membrane. Is expressed in brain and lung. Orthologous to human DEPTOR (DEP domain containing MTOR interacting protein). PHENOTYPE: Homozygous conditional KO in the liver results in lower hepatic glycogen content and increased oxidative metabolism in fasted mice. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
