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Protein Coding Gene : Hdac7 histone deacetylase 7

Primary Identifier  MGI:1891835 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  56233
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables chromatin binding activity; histone deacetylase activity; and transcription corepressor activity. Acts upstream of or within cell-cell junction assembly; negative regulation of transcription by RNA polymerase II; and vasculogenesis. Is active in nucleus. Is expressed in several structures, including adrenal gland; heart; and sensory organ. Orthologous to human HDAC7 (histone deacetylase 7).
PHENOTYPE: Deletion of this gene result in embryonic lethality by E11, due to vascular defects which are due to endothelial cell adhesion defects. [provided by MGI curators]
  • synonyms:
  • Hdac7,
  • MGI:2443780,
  • 5830434K02Rik,
  • histone deacetylase 7,
  • RIKEN cDNA 5830434K02 gene,
  • Hdac7a

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

9 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For