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ncRNA Gene : Hotair HOX transcript antisense RNA (non-protein coding)
Primary Identifier  MGI:3826586 Organism  mouse, laboratory
Chromosome  15 NCBI Gene Number  100503872
Mgi Type  lncRNA gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Involved in hindlimb morphogenesis and post-anal tail morphogenesis. Acts upstream of or within heterochromatin formation and skeletal system development. Located in chromosome. Is active in nucleus. Is expressed in several structures, including gonad; hindlimb bud; limb; tail; and trunk. Orthologous to human HOTAIR (HOX transcript antisense RNA).
PHENOTYPE: Homozygous inactivation of this gene results in caudal vertebral transformation. Additional phenotypes may include lumbar vertebral transformation and structural malformations of the metacarpal-carpal bones, tail and hind limbs. [provided by MGI curators]
  • synonyms:
  • Gm16258,
  • predicted gene, OTTMUSG00000032781,
  • OTTMUSG00000032781,
  • HOX transcript antisense RNA (non-protein coding),
  • Hotair,
  • predicted gene 16258
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3 Involved In Mutations

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0 Transgenic Expressors

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

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Disease

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