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Protein Coding Gene : Eci1 enoyl-Coenzyme A delta isomerase 1

Primary Identifier  MGI:94871 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  13177
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables delta(3)-delta(2)-enoyl-CoA isomerase activity. Acts upstream of or within fatty acid beta-oxidation. Located in mitochondrial inner membrane. Is expressed in testis. Orthologous to human ECI1 (enoyl-CoA delta isomerase 1).
PHENOTYPE: Mice homozygous for disruption of this gene are normal until stressed. Starvation results in increased accumulation of triglycerides and unsaturated fatty acids in the liver and kidney. Secretion of fatty acid metabolites in the urine is greatly increased. [provided by MGI curators]
  • synonyms:
  • Dci,
  • eci,
  • MGD-MRK-8810,
  • Eci1,
  • dodecenoyl-Coenzyme A delta isomerase (3,2 trans-enoyl-Coenyme A isomerase),
  • enoyl-Coenzyme A delta isomerase 1

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For