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Protein Coding Gene : Sik1 salt inducible kinase 1

Primary Identifier  MGI:104754 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  17691
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables several functions, including cAMP response element binding protein binding activity; enzyme binding activity; and ion binding activity. Involved in several processes, including anoikis; entrainment of circadian clock by photoperiod; and negative regulation of cellular biosynthetic process. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; heart; and sensory organ. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 30. Orthologous to human SIK1 (salt inducible kinase 1).
PHENOTYPE: Mice homozygous for a knock-out allele and fed a high fat diet exhibit increased insulin sensitivity. [provided by MGI curators]
  • synonyms:
  • Msk,
  • MGD-MRK-28045,
  • salt inducible kinase 1,
  • SNF1-like kinase,
  • myocardial SNF1-like kinase,
  • Snf1lk,
  • Sik1

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For