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Protein Coding Gene : Mad2l1bp MAD2L1 binding protein
Primary Identifier  MGI:1913841 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  66591
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to be involved in deactivation of mitotic spindle assembly checkpoint and regulation of exit from mitosis. Predicted to act upstream of or within mitotic spindle assembly checkpoint signaling. Predicted to be located in cytoplasm and nucleus. Predicted to be active in nucleus. Orthologous to human MAD2L1BP (MAD2L1 binding protein).
PHENOTYPE: Mice homozygous for a knock-out allele show fetal growth retardation, complete neonatal lethality, and decreased liver glycogen level. Mouse embryonic fibroblasts exhibit mitotic and aneuploidy phenotypes. [provided by MGI curators]
  • synonyms:
  • expressed sequence AW550977,
  • MGI:1923838,
  • 0610009D16Rik,
  • 2510031P20Rik,
  • AW550977,
  • Mad2l1bp,
  • MGI:2146978,
  • AU018945,
  • CMT2B,
  • MAD2L1 binding protein,
  • RIKEN cDNA 2510031P20 gene,
  • CMT2A,
  • expressed sequence C76045,
  • RIKEN cDNA 0610009D16 gene,
  • expressed sequence AU018945,
  • MGI:2147112,
  • C76045,
  • MGI:2147084
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