| Primary Identifier | MGI:2146974 | Organism | Mus musculus |
| Chromosome | 17 | NCBI Gene Number | 224903 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 3.2) Exhibits RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and chromatin binding activity. Involved in several processes, including hormone metabolic process; intracellular estrogen receptor signaling pathway; and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleoplasm. Is expressed in several structures, including central nervous system; future brain; olfactory epithelium; reproductive system; and retina layer. Orthologous to human SAFB (scaffold attachment factor B). PHENOTYPE: Homozygous null mice display partial embryonic and neonatal lethality, neonatal cyanosis, impaired embryonic hematopoiesis, male sterility, azoospermia, reduced female fertility, impaired transport of embryos through the oviduct, reduced embryonic growth, testicular degeneration and ovarian atrophy. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
