| Primary Identifier | MGI:1195273 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 21948 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable cytokine activity and protease binding activity. Predicted to be involved in several processes, including B cell proliferation; T cell mediated immunity; and extrinsic apoptotic signaling pathway. Predicted to be located in extracellular space and membrane. Predicted to be active in plasma membrane. Is expressed in Meckel's cartilage; hip; and skeleton. Human ortholog(s) of this gene implicated in lymphoproliferative syndrome. Orthologous to human CD70 (CD70 molecule). PHENOTYPE: Expansion of CD8+ cells after viral expansion is significantly less in mice with a homozygous deletion than in controls. However, the restimulation response is comparable to controls. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
