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Protein Coding Gene : Lpin2 lipin 2

Primary Identifier  MGI:1891341 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  64898
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables phosphatidate phosphatase activity and transcription coactivator activity. Involved in positive regulation of transcription by RNA polymerase II and triglyceride biosynthetic process. Located in cytosol and endoplasmic reticulum membrane. Is expressed in central nervous system; gonad; liver; lung; and retina. Orthologous to human LPIN2 (lipin 2).
PHENOTYPE: Homozygous null mice develop ataxia, impaired blance, and tremors with age and show altered cerebellar phospholipid composition and anemia. Mice show diet-induced hepatic triglyceride accumulation. [provided by MGI curators]
  • synonyms:
  • expressed sequence AW742896,
  • AI481352,
  • MGI:2146881,
  • MGI:1915262,
  • 2610511G02Rik,
  • MGI:2147099,
  • RIKEN cDNA 2610511G02 gene,
  • expressed sequence AI481352,
  • lipin 2,
  • Lpin2,
  • AW742896

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

14 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For