| Primary Identifier | MGI:1913560 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 66310 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable protein homodimerization activity. Predicted to be involved in endosomal transport and transcription initiation-coupled chromatin remodeling. Predicted to act upstream of or within chromatin organization. Predicted to be located in nucleoplasm and trans-Golgi network. Predicted to be part of MLL1 complex; MLL3/4 complex; and Set1C/COMPASS complex. Is expressed in several structures, including alimentary system; cerebral cortex; lung; nose; and submandibular gland primordium. Orthologous to human DPY30 (dpy-30 histone methyltransferase complex regulatory subunit). PHENOTYPE: Embryos homozygous for a knock-out allele die between E7.5 and E9.5 exhibiting abnormal post-implantation development associated with absence of the primitive streak and impaired gastrulation of the pluripotent epiblast. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
