Primary Identifier | MGI:99462 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 18701 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable mannose-ethanolamine phosphotransferase activity. Involved in GPI anchor biosynthetic process. Located in endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; brain; respiratory system; sensory organ; and urinary system. Orthologous to human PIGF (phosphatidylinositol glycan anchor biosynthesis class F). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal placenta morphology and complete lethality throughout fetal growth and development. [provided by MGI curators] |