Primary Identifier | MGI:2447322 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 192161 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable calcium ion binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within several processes, including apoptotic process; cell population proliferation; and heart development. Located in membrane. Is active in cell-cell contact zone. Is expressed in brain and gut. Orthologous to human PCDHA10 (protocadherin alpha 10). PHENOTYPE: Mice homozygous for an ENU-induced mutation exhibit cardiac hypertrophy, aorta hypoplasia and stenosis, and bicuspid aortic valve. [provided by MGI curators] |