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Protein Coding Gene : Impa2 inositol monophosphatase 2

Primary Identifier  MGI:2149728 Organism  Mus musculus
Chromosome  18 NCBI Gene Number  114663
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 3.2)

Predicted to have inositol monophosphate 1-phosphatase activity and protein homodimerization activity. Predicted to be involved in inositol metabolic process; inositol phosphate dephosphorylation; and signal transduction. Predicted to localize to cytoplasm. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in bipolar disorder and schizophrenia. Orthologous to human IMPA2 (inositol monophosphatase 2).
PHENOTYPE: Mice homozygous for a null gene trap mutation do not exhibit an overt mutant phenotype. Male mice homozygous for a knock-out alle exhibit increased prepulse inhibition. [provided by MGI curators]
  • synonyms:
  • expressed sequence AW259601,
  • MGI:2147214,
  • AW259601,
  • AI326924,
  • 2210415D20Rik,
  • RIKEN cDNA 2210415D20 gene,
  • MGI:2147360,
  • inositol monophosphatase 2,
  • expressed sequence AI326924,
  • MGI:1917400,
  • Impa2,
  • inositol (myo)-1(or 4)-monophosphatase 2

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

88 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Mouse features --> Alleles

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications