Primary Identifier | MGI:103073 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 22786 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable acrosin binding activity. Predicted to be a structural constituent of egg coat. Predicted to be involved in binding activity of sperm to zona pellucida and prevention of polyspermy. Predicted to act upstream of or within single fertilization. Located in collagen-containing extracellular matrix. Is expressed in early conceptus; ovary; and secondary oocyte. Orthologous to human ZP1 (zona pellucida glycoprotein 1). PHENOTYPE: Female homozygous mutants produce oocytes with abnormal zona pellucida. Fecunditiy is significantly reduced, probably due to precocious hatching. [provided by MGI curators] |