|  Help  |  About  |  Contact Us

Protein Coding Gene : Dmrt3 doublesex and mab-3 related transcription factor 3

Primary Identifier  MGI:2449470 Organism  mouse, laboratory
Chromosome  19 NCBI Gene Number  240590
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables sequence-specific DNA binding activity. Acts upstream of or within several processes, including adult walking behavior; regulation of odontogenesis of dentin-containing tooth; and ventral spinal cord interneuron specification. Located in nucleus. Is expressed in several structures, including adrenal gland; alimentary system; central nervous system; genitourinary system; and nose. Orthologous to human DMRT3 (doublesex and mab-3 related transcription factor 3).
PHENOTYPE: Mice homozygous for a knock-out allele die from starvation at 2 months of age due to dental malocclusions; some males exhibit defects in sexual development. Mutant mice also exhibit locomotor abnormalities. Mice homozygous for a different knock-out allele exhibit decreased neocortex area. [provided by MGI curators]
  • synonyms:
  • Dmrt3,
  • doublesex and mab-3 related transcription factor 3

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For