| Primary Identifier | MGI:1918483 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 71233 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables calmodulin binding activity. Acts upstream of or within establishment of left/right asymmetry and flagellated sperm motility. Located in 9+0 motile cilium; acrosomal vesicle; and sperm principal piece. Is active in axonemal B tubule inner sheath. Is expressed in lung; node; testis; and trachea. Orthologous to human ENKUR (enkurin, TRPC channel interacting protein). PHENOTYPE: Some mice homozygous for a null allele exhibit situs invertus or situs ambiguus. Males show subfertility, impaired sperm migration in female genital tract, nonprogressive sperm motility with an asymmetric flagellar waveform, a low fertility rate, and loss of Ca2+-responsiveness after demembranation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
