Primary Identifier | MGI:1351631 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 27387 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable transmembrane receptor protein tyrosine kinase adaptor activity. Predicted to be involved in positive regulation of peptidyl-serine phosphorylation. Predicted to act upstream of or within cell surface receptor protein tyrosine kinase signaling pathway. Predicted to be located in cytosol. Orthologous to human SH2D3C (SH2 domain containing 3C). PHENOTYPE: Mice homozygous for a knock-out allele exhibit neonatal lethality with absence of gastric milk. Surviving mice exhibit abnormal olfactory bulb innervation, fewer gonadotrophin positive cells in the hypothalamus, and decreased testes size. [provided by MGI curators] |