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Protein Coding Gene : Sh2d3c SH2 domain containing 3C

Primary Identifier  MGI:1351631 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  27387
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable transmembrane receptor protein tyrosine kinase adaptor activity. Predicted to be involved in positive regulation of peptidyl-serine phosphorylation. Predicted to act upstream of or within cell surface receptor protein tyrosine kinase signaling pathway. Predicted to be located in cytosol. Orthologous to human SH2D3C (SH2 domain containing 3C).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit neonatal lethality with absence of gastric milk. Surviving mice exhibit abnormal olfactory bulb innervation, fewer gonadotrophin positive cells in the hypothalamus, and decreased testes size. [provided by MGI curators]
  • synonyms:
  • Chat,
  • Nsp3,
  • Shep1,
  • SH2-containing Eph receptor-binding protein 1,
  • SH2 domain containing 3C,
  • novel SH2-containing protein 3,
  • Sh2d3c,
  • Cas/HEF1-associated signal transducer

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

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Genes --> Homologs

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Gene --> Expression annotations

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Disease

Mouse features --> Human diseases

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