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Protein Coding Gene : Strbp spermatid perinuclear RNA binding protein

Primary Identifier  MGI:104626 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  20744
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables double-stranded RNA binding activity; microtubule binding activity; and single-stranded RNA binding activity. Acts upstream of or within cell motility; mechanosensory behavior; and spermatid development. Located in manchette. Is expressed in central nervous system; dorsal root ganglion; metanephros; sensory organ; and trigeminal nerve. Orthologous to human STRBP (spermatid perinuclear RNA binding protein).
PHENOTYPE: Mice homozygous for a gene trap insertion exhibit premature death, a reduced body size and an abnormal clutching reflex. Minor brain abnormalities and spermatogenesis defects were also noted. [provided by MGI curators]
  • synonyms:
  • C86322,
  • Strbp,
  • C230082I21Rik,
  • MGI:2139526,
  • spermatid perinuclear RNA binding protein,
  • AI852513,
  • Spnr,
  • MGD-MRK-26063,
  • RIKEN cDNA C230082I21 gene,
  • MGI:2139088,
  • expressed sequence C86322,
  • expressed sequence AI852513,
  • 6430510M02Rik,
  • MGI:2442183,
  • RIKEN cDNA 6430510M02 gene

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