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Protein Coding Gene : Scai suppressor of cancer cell invasion
Primary Identifier  MGI:2443716 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  320271
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables transcription corepressor activity. Involved in negative regulation of Rho protein signal transduction and negative regulation of cell migration. Located in cytoplasm and nucleus. Is expressed in olfactory epithelium. Orthologous to human SCAI (suppressor of cancer cell invasion).
PHENOTYPE: Homozygous mice of both sexes are sub-fertile owing to compromised meiotic synapsis and homologous recombination-mediated double-strand break DNA repair. [provided by MGI curators]
  • synonyms:
  • AI662729,
  • expressed sequence AI662729,
  • RIKEN cDNA A930041I02 gene,
  • A930041I02Rik,
  • MGI:2139039,
  • suppressor of cancer cell invasion,
  • Scai
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