| Primary Identifier | MGI:1858234 | Organism | mouse, laboratory |
| Chromosome | 2 | NCBI Gene Number | 53872 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable several functions, including ATP binding activity; molecular condensate scaffold activity; and signaling adaptor activity. Involved in positive regulation of dendritic spine morphogenesis. Acts upstream of or within generation of neurons; intracellular mRNA localization; and synapse assembly. Located in cytoplasmic stress granule. Is active in dendrite and synapse. Is expressed in central nervous system; eye; and genitourinary system. Orthologous to human CAPRIN1 (cell cycle associated protein 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased fetal size, bent posture, cyanosis, respiratory failure, and neonatal lethality with impaired neuronal network development and reduced dendritic localization of sodium potassium ATPase subunit isoform mRNAs. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
