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Protein Coding Gene : Lmo2 LIM domain only 2

Primary Identifier  MGI:102811 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  16909
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables chromatin binding activity. Contributes to DNA binding activity. Involved in negative regulation of erythrocyte differentiation. Acts upstream of or within embryonic hemopoiesis and positive regulation of transcription by RNA polymerase II. Located in nucleus. Part of protein-containing complex. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human LMO2 (LIM domain only 2).
PHENOTYPE: Homozygotes for a targeted null mutation exhibit lack of yolk sac erythropoiesis and die around embryonic day 10.5. [provided by MGI curators]
  • synonyms:
  • Rbtn2,
  • MGD-MRK-13800,
  • LIM domain only 2,
  • Rhom-2,
  • rhombotin 2,
  • MGD-MRK-19719,
  • MGD-MRK-13797,
  • Lmo2,
  • Rbtn-2

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For