Primary Identifier | MGI:1346051 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 110074 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable several functions, including dUTP diphosphatase activity; peroxisome proliferator activated receptor binding activity; and pyrimidine deoxyribonucleotide binding activity. Predicted to be involved in pyrimidine deoxyribonucleotide metabolic process and regulation of protein-containing complex assembly. Predicted to act upstream of or within nucleotide metabolic process. Located in mitochondrion. Is expressed in central nervous system and retina. Orthologous to human DUT (deoxyuridine triphosphatase). PHENOTYPE: Mice homozygous for a null allele die shortly after implantation and embryos show smaller inner cell mass and trophectoderm size when grown in vitro. [provided by MGI curators] |