Primary Identifier | MGI:2158650 | Organism | mouse, laboratory |
Chromosome | 2 | NCBI Gene Number | 170718 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable isocitrate dehydrogenase (NAD+) activity. Predicted to be involved in NADH metabolic process; carboxylic acid metabolic process; and tricarboxylic acid cycle. Located in mitochondrion. Part of isocitrate dehydrogenase complex (NAD+). Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in retinitis pigmentosa 46. Orthologous to human IDH3B (isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta). PHENOTYPE: Homozygous knockout does not cause eye phenotypes. [provided by MGI curators] |