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Protein Coding Gene : a nonagouti

Primary Identifier  MGI:87853 Organism  Mus musculus
Chromosome  2 NCBI Gene Number  50518
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources

Exhibits type 3 melanocortin receptor binding activity and type 4 melanocortin receptor binding activity. Involved in several processes, including adult feeding behavior; melanosome transport; and positive regulation of melanin biosynthetic process. Used to study obesity and type 2 diabetes mellitus. Is expressed in hair bulb and skin. Orthologous to human ASIP (agouti signaling protein).
PHENOTYPE: Agouti acts in the hair follicles, primarily affecting the relative amount and distribution of yellow pigment (phaeomelanin) and black pigment (eumelanin) in hairs of the coat. Some alleles show lethal effects or are associated with obesity. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-1002,
  • MGD-MRK-1397,
  • ASP,
  • MGD-MRK-1008,
  • agouti signal protein,
  • a,
  • agouti,
  • agouti suppressor,
  • nonagouti,
  • As

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

3 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

20 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Mouse features --> Alleles

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications